You see every day, people all over the planet are searching for different things on the internet, and rather than trying to advertise your new, great sounding site name to them, just use what they are searching for the most.
If your site sold winter clothes and someone wants to buy fish food, do you think they will type “winterforeveryone.com” into their browser, no, they type winter clothes, so wouldn’t it make sense to have the domain name “winterclothes.com.
Having your main keywords in the domain name is also SE friendly and could deliver a better ranking for your website.
It would also be an idea to combine your unique name, for example “meho” and the word that is part of what your site offers. For example “mehoclothes.com”. That makes sense too.
My suggestion on how to pick a good domain name is the following:
nounnoun.com
uniquenamenouncom
verbkeyword.com
pronounnoun.com
nounpronoun.com
It also comes to domain extension, or commonly known as TLD. Probably the best idea is choosing a .com. If you’re not selling anything or your site is simply caritable, then it will be more user-friendly to use a .org. But I would recommend never using a .info or a .biz.
Either use a .com is your name is available, .org if you don’t sell anything, .countrycode if you are a local based company or you are the market leader for the certain niche of the site in your country, and use .net when your .com isn’t available 
